Proteins that are attached to DNA

[GenesForLife]

I've also uploaded a Bioinformatics textbook here for download and reference, link is http://www.4shared.com/document/dxpvPon ... nd_Ge.html

[Dory]

Oh you're good. You're really good.

I love it how I'm on the verge of knowledge of just having enough to catch up with you...just hardly. That makes chasing what you say exciting and research-worthy.

It's all fucking fascinating. First off I just found out that Hox genes " are a group of related genes that specify the anterior-posterior axis and segment identity of metazoan organisms during early embryonic development." It's cool to find out just how mutually exclusive genes are, and shows that it's the Hox genes probably made the insects, worms, and all other segmented creatures quite successful. Evolution surely loves segmentation.

I've been following up with you as far as the antibiotics protein. Where can I find its DNA in FASTA form?

It looks like the sequence that was analyzed either underwent Horizontal Gene Transfer between Klebsiella and E.coli or diverged from an ancestral sequence present in a concestor (which can be confirmed by checking out their taxonomic relationship, which the tree indicates is close as both are enterobacteria.

I love this shit! Horizontal Gene Transfer doesn't sound very specific, but who am I to critique this thing...I'm just getting to know it!

I'm downloading your document

[GenesForLife]

To view the FASTA form, go to the database entry page, here is a mouse hox gene, for example.

http://www.ncbi.nlm.nih.gov/nuccore/NM_010466.2

At the top there is a dropdown setting called Display Settings, currently marked GenBank (which is the nucleotide sequence databank)
, click the dropdown arrow, click the radio button titled FASTA / FASTA (text)

This is what you get

http://www.ncbi.nlm.nih.gov/nuccore/NM_ ... ormat=text

FASTA is important because a lot of alignment tools use it , the '>' is the identifier.

That is it, I'd recommend that you try viewing it in all possible formats and get back if you find anything particularly interesting/question worthy.

[GenesForLife]

I love this shit! Horizontal Gene Transfer doesn't sound very specific, but who am I to critique this thing...I'm just getting to know it!

I'm downloading your document

Well, bacteria have been known to share plasmids across species , if , say, we find a closely related sequence in unrelated bacteria, there is every possibility that the gene may have been transferred horizontally, usually, when the sequence homology matches relationship, it can be inferred that the ancestral gene X in organism Y was conserved in descendants Y1 and Y2, Horizontal Gene Transfer, as far as I know, is limited to bacteria and viruses.

[Dory]

Thanks, awesome! Can I ask what do you do for a living Genes? Do you work in science?

[GenesForLife]

Thanks, awesome! Can I ask what do you do for a living Genes?

Just graduated with a B.Sc in Biotechnology, Biochemistry and Microbiology , am waiting for Visa clearance to go to the UK to study Cancer Biology at UCL.

[Dory]

Thanks, awesome! Can I ask what do you do for a living Genes?

Just graduated with a B.Sc in Biotechnology, Biochemistry and Microbiology , am waiting for Visa clearance to go to the UK to study Cancer Biology at UCL.

With that frown, you're going places.

[GenesForLife]

Thanks, awesome! Can I ask what do you do for a living Genes?

Just graduated with a B.Sc in Biotechnology, Biochemistry and Microbiology , am waiting for Visa clearance to go to the UK to study Cancer Biology at UCL.

With that frown, you're going places.

Its use is limited to certain situations.

[Xamonas Chegwé]

Thanks, awesome! Can I ask what do you do for a living Genes?

Just graduated with a B.Sc in Biotechnology, Biochemistry and Microbiology , am waiting for Visa clearance to go to the UK to ATTEND A RATZ MEET!!1!

[GenesForLife]

Thanks, awesome! Can I ask what do you do for a living Genes?

Just graduated with a B.Sc in Biotechnology, Biochemistry and Microbiology , am waiting for Visa clearance to go to the UK to ATTEND A RATZ MEET!!1!

Will be part of my iterinary.

[Xamonas Chegwé]

Thanks, awesome! Can I ask what do you do for a living Genes?

Just graduated with a B.Sc in Biotechnology, Biochemistry and Microbiology , am waiting for Visa clearance to go to the UK to ATTEND A RATZ MEET!!1!

Will be part of my iterinary.

Best of luck, GFL. This is relevant to our interests!

[SevenOfNine]

Lurking in this thread, GFL is a mine of good info, I want to have h** baby!

Apart from that, if you stay at a UCL college, I would recommend Ian Baker House [Access via Ramsay House]. There is a modern wing where the facilities are superior. It is a bit more expensive, but well worth it.
[Depending if you are a light sleeper or not, or if you can concentrate in noisy environments]

However, some college kids tend to be a bit noisy sometimes, and they organize disco/dance/etc two or three times a week. So stay with family or friends if you can.

[Dory]

I'm a bit struggling with this bioinformatics. Though it's cool and interesting, since I'm not gonna have an exam over it and since it's tough to figure out on my own (no, I didn't read that 500-pages ebook!) I think I'll put it on the backburner for now. But it's definitely a cool tool. GFL is a great catch.

[GenesForLife]

Lurking in this thread, GFL is a mine of good info, I want to have h** baby!

Apart from that, if you stay at a UCL college, I would recommend Ian Baker House [Access via Ramsay House]. There is a modern wing where the facilities are superior. It is a bit more expensive, but well worth it.
[Depending if you are a light sleeper or not, or if you can concentrate in noisy environments]

However, some college kids tend to be a bit noisy sometimes, and they organize disco/dance/etc two or three times a week. So stay with family or friends if you can.

Have asked for Ensuite self catered facilities, mate, Gardner, Goldsmid, Lighthill, Dodgson and Prankered.

[GenesForLife]

I'm a bit struggling with this bioinformatics. Though it's cool and interesting, since I'm not gonna have an exam over it and since it's tough to figure out on my own (no, I didn't read that 500-pages ebook!) I think I'll put it on the backburner for now. But it's definitely a cool tool. GFL is a great catch.

Well Dory, it is only a bit difficult when you begin to just get acquainted with tools just like that, I should've started with sequences and what we could do with them

PS - Does that mean I don't get to teach you sequence analysis for now ? If so I need to find another pastime.