Origin of ribose explained. Talk origins has the jpg
The five membered heterocycle reacts with the three carbon aldehyde. The original thinking is crossed out., adenine plus ribose.
Paper was in
Szostak JW (2009) Systems chemistry on early Earth. Nature 459: 171-172
I've lost the talk origins page but Szostak should locate it.
Ribose
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Ribose
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Said Peter...what you're requesting just isn't my bag
Said Daemon, who's sorry too, but y'see we didn't have no choice
And our hands they are many and we'd be of one voice
We've come all the way from Wigan to get up and state
Our case for survival before it's too late
Turn stone to bread, said Daemon Duncetan
Turn stone to bread right away...
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Re: Ribose
Sorry. Cytosine plus ribose, the way we would put the parts together in the lab. It's neat that the phosphate is part of the mechanism of opening the tricyclic intermediate to cytidine.
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http://esabirdsne.blogspot.com/
Said Peter...what you're requesting just isn't my bag
Said Daemon, who's sorry too, but y'see we didn't have no choice
And our hands they are many and we'd be of one voice
We've come all the way from Wigan to get up and state
Our case for survival before it's too late
Turn stone to bread, said Daemon Duncetan
Turn stone to bread right away...
http://esabirdsne.blogspot.com/
Said Peter...what you're requesting just isn't my bag
Said Daemon, who's sorry too, but y'see we didn't have no choice
And our hands they are many and we'd be of one voice
We've come all the way from Wigan to get up and state
Our case for survival before it's too late
Turn stone to bread, said Daemon Duncetan
Turn stone to bread right away...
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Re: Ribose
After the first billion years.
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Re: Ribose
We had to evolve ribonucleotide reductase first. It takes the ribose nucleotides and plucks off the 2-OH. See Wiki for the enzyme. Or google JoAnne Stubbe.
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