Ribose

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Tero
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Ribose

Post by Tero » Wed Jun 19, 2013 1:30 am

Origin of ribose explained. Talk origins has the jpg
Image

The five membered heterocycle reacts with the three carbon aldehyde. The original thinking is crossed out., adenine plus ribose.
Paper was in
Szostak JW (2009) Systems chemistry on early Earth. Nature 459: 171-172

I've lost the talk origins page but Szostak should locate it.
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Re: Ribose

Post by Tero » Wed Jun 19, 2013 3:15 am

Sorry. Cytosine plus ribose, the way we would put the parts together in the lab. It's neat that the phosphate is part of the mechanism of opening the tricyclic intermediate to cytidine.
International disaster, gonna be a blaster
Gonna rearrange our lives
International disaster, send for the master
Don't wait to see the white of his eyes
International disaster, international disaster
Price of silver droppin' so do yer Christmas shopping
Before you lose the chance to score (Pembroke)

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Re: Ribose

Post by JimC » Wed Jun 19, 2013 4:23 am

Can I have mine de-oxyed, please... :tea:
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Re: Ribose

Post by Tero » Wed Jun 19, 2013 11:36 am

After the first billion years.

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Re: Ribose

Post by Tero » Wed Jun 19, 2013 12:49 pm

We had to evolve ribonucleotide reductase first. It takes the ribose nucleotides and plucks off the 2-OH. See Wiki for the enzyme. Or google JoAnne Stubbe.

I'm one handshake away from Obama via her. I have one or two papers with her.

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