Ethical human testing

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Sean Hayden
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Ethical human testing

Post by Sean Hayden » Wed Sep 04, 2019 3:25 am

It's too slow. If you aren't doing unethical testing with the latest in say genetics, then the other guy is. So, who are they testing on? What do they hope to achieve?

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Re: Ethical human testing

Post by Sean Hayden » Wed Sep 04, 2019 4:41 am

Nothing? Okay, I'll go first. A unique identifier placed on a significant number of brain cells via a virus. It would probably be necessary for the identifier to be unknown initially, but easily discoverable upon screening. Now you're mapping to an incredible level of detail. Go hunting for patterns!

Can you engineer a virus to work with those cells identified in a pattern so as to be able to add the capability of firing that pattern?
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Re: Ethical human testing

Post by pErvinalia » Wed Sep 04, 2019 6:59 am

What?
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Re: Ethical human testing

Post by JimC » Wed Sep 04, 2019 7:02 am

Galaxian will tell you that it's already been done by his alien buddies...
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Re: Ethical human testing

Post by laklak » Wed Sep 04, 2019 7:50 am

That's why the Chinee are making monkeymen.
Yeah well that's just, like, your opinion, man.

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Re: Ethical human testing

Post by Brian Peacock » Wed Sep 04, 2019 9:04 am

Regardless of whether it's being done already there's no ethical argument that proposes we have to do it because somebody else is already at it, or we have to do it now before somebody else. Unless, that is, you view knowledge, it's acquisition and exploitation, as a commodity.

With regards to experiments and/or procedures to manipulate or transpose gene expression, how can you give informed consent on behalf of your yet to be conceived off-spring?

I don't know - but when they can do it I want to be able to purr like a big man-kitten.
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Re: Ethical human testing

Post by Sean Hayden » Wed Sep 04, 2019 10:48 am

It's the new arms race Peacock, therefore national security, and everything is right with the world again.
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Re: Ethical human testing

Post by Sean Hayden » Wed Sep 04, 2019 11:00 am

JimC wrote:
Wed Sep 04, 2019 7:02 am
Galaxian will tell you that it's already been done by his alien buddies...
Aliens, pfft.
The main challenge before optogenetic therapies become a reality is getting opsin genes into the adult human neurons to be targeted in a treatment. In rodents researchers have employed two main strategies: transgenics, in which mice are bred to make opsins in specific neurons—an option unsuitable for use in humans. The other method uses a virus to implant a gene into a neuron. Viruses are currently being used for other types of gene therapy in humans, but challenges remain. Viruses must penetrate mature neurons and deliver their gene cargo without spurring an immune reaction. Then the neuron has to express the opsin in the right place, and it has to go on making the protein continuously—ideally forever.

Delp and others have achieved pain relief in rodents following viral delivery by activating the opsin to shut down a pain-producing circuit. “Two weeks after a single injection of virus containing a gene for an inhibitory opsin into the peripheral nerve, we see robust expression of opsin in neurons all the way down to the skin. All we have to do is illuminate the skin and we can suppress painful touch and heat sensitivity—a major symptomatic problem in humans with chronic pain,” Delp says. Whether the technique will actually work in people remains to be seen.
https://www.scientificamerican.com/arti ... al-trials/

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Re: Ethical human testing

Post by Brian Peacock » Wed Sep 04, 2019 11:33 am

Sean Hayden wrote:
Wed Sep 04, 2019 10:48 am
It's the new arms race Peacock, therefore national security, and everything is right with the world again.
That's just your Imperialist conditioning kicking in and telling you that corporatism is the only legitimate form of patriotism. :D
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Clinton Huxley » 21 Jun 2012 » 14:10:36 GMT
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Re: Ethical human testing

Post by Tero » Wed Sep 04, 2019 12:11 pm

Just put it in sone Monsanto GMO crops. Then we can all test it together. "Corn starch, yum!" "GMO lentils with added hemoglobin, yum!"
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