The Coronavirus Thread

[JimC]

I don't think this virus gives a shit about the seasons...

[Brian Peacock]

Astrology is complete and utter bunkum - but I'm a Pisces, so I would say that.

Weird so am I. February Pisces are you? I am a March Pisces.

March. All the best Pisces are you know.

[Tero]

Wikipedia ha pandemic pages for a number of areas. I addition there is a virus page that gets new info weekly.
https://en.wikipedia.org/wiki/Coronavirus_disease_2019

https://en.wikipedia.org/wiki/Coronavir ... 19#Vaccine
https://en.wikipedia.org/wiki/COVID-19_ ... ed_in_2020

--> https://www.who.int/publications/m/item ... e-vaccines
that gives a pdf download
it's just a list with no commets, but is more extensive than the Wiki list

Back to Wiki, success and then % of people covered once approved is going to be modest:

Industry analysis of past vaccine development shows failure rates of 84-90%.[4][51] Because COVID‑19 is a novel virus target with properties still being discovered and requiring innovative vaccine technologies and development strategies, the risks associated with developing a successful vaccine across all steps of preclinical and clinical research are high.[4]

To assess potential for vaccine efficacy, unprecedented computer simulations and new COVID‑19-specific animal models are being developed multinationally during 2020, but these methods remain untested by unknown characteristics of the COVID‑19 virus.[4] Of the confirmed active vaccine candidates, about 70% are being developed by private companies, with the remaining projects under development by academic, government coalitions, and health organizations.[4]

Most of the vaccine developers are small firms or university research teams with little experience in successful vaccine design and limited capacity for advanced clinical trial costs and manufacturing without partnership by multinational pharmaceutical companies.[4] The general geographic distribution of COVID‑19 vaccine development involves organizations in the United States and Canada, together having about 46% of the world's active vaccine research, compared with 36% in Asian countries, including China, and 18% in Europe.[4]

By July, one organization reported that 205 vaccine candidates were in development as either "exploratory/preclinical" projects or in Phase I-III trials in human participants.[8] The table in this section lists emerging vaccine candidates whose Phase I trial starts are scheduled in 2020.

Scheduled Phase I trials in 2020
Many vaccine candidates under design or preclinical development for COVID‑19 will not gain approval for human studies in 2020 due to toxicity, ineffectiveness to induce immune responses or dosing failures in laboratory animals, or because of underfunding.[89][90] The probability of success for an infectious disease vaccine candidate to pass preclinical barriers and reach Phase I of human testing is 41-57%.[89]

Commitment to first-in-human testing of a vaccine candidate represents a substantial capital cost for vaccine developers, estimated to be from US$14 million to US$25 million for a typical Phase I trial program, but possibly as much as US$70 million.[89][91] For comparison, during the Ebola virus epidemic of 2013-16, there were 37 vaccine candidates in urgent development, but only one eventually succeeded as a licensed vaccine, involving a total cost to confirm efficacy in Phase II–III trials of about US$1 billion.[89]

[DRSB]

Astrology is complete and utter bunkum - but I'm a Pisces, so I would say that.

Weird so am I. February Pisces are you? I am a March Pisces.

March. All the best Pisces are you know.

Me too.

[Scot Dutchy]

I am the second.

[laklak]

March Pisces here too. We the best.

[Scot Dutchy]

Quite strange or not?
Are Pisceans more attracted to fora? Hey Jim what are you?

[laklak]

I think it's those hot summer nights 9 months before.

[Brian Peacock]

I was a miracle child. My parents had only been married 5 months when I was born, so I must have been conceived in October following their nuptials.

[DRSB]

I identify rather as monkey, Chinese astrology.

[Scot Dutchy]

I think it's those hot summer nights 9 months before.

Holidays lak. My mum and dad had their first holiday by friends in Virginia Waters. It was outside London.

[Tero]

I was a miracle child. My parents had only been married 5 months when I was born, so I must have been conceived in October following their nuptials.

Somewhere I have my dead parents' marriage certificate. I didn't do the math but it was similar.

I also remember my mom taken away by ambulance when I was 10. Then she came back the next day and cooked dinner. It took me years to figure out she had a miscarriage.

[Sean Hayden]

I identify rather as monkey, Chinese astrology.

I'm a bull.



...and a snake if we're using Chinese astrology.

[JimC]

Quite strange or not?
Are Pisceans more attracted to fora? Hey Jim what are you?

Capricorn...

[Tero]

More on antibody after infection
https://thehill.com/policy/healthcare/5 ... rs-say?amp